The News Review:

- Dennis Gillings
- Medicus completes Mint Medical acquisition
- The Galveston County Daily News
- Pact on ‘bench to bedside’ research system
- pen source drug discovery
- Wyeth Will Pursue Claim for Damages Resulting From Teva Pharmaceutical…
- Favorable review for RPCI frees up funding

Dennis Gillings
Bizjournals.com – Dec 24, 2007
This say Gillings' students is the sum of their teacher's two careers. Numbers gleaned from research must be used to find real-world solutions. For founding and then building the largest clinical research organization in the world for keeping that organization in the Triangle and for giving UNC the largest philanthropic gift in its history Dennis Gillings is Triangle Business Journal's 2007 Businessperson of the Year. Dennis Gillings was born on April 25 1944 in World War II London. He credits his father a fishmonger who was "quick with numbers" for nurturing his interest in mathematics at a young age. Gillings went on to earn a bachelor's degree in mathematics from the University of Exeter and the equivalent of a master's degree in mathematical statistics from the University of Cambridge. He then returned to the University of Exeter where he taught while earning his doctorate in mathematics.

Medicus completes Mint Medical acquisition
Bizjournals.com – Dec 21, 2007
Mint Medical which does business as. "This change in ownership will allow our executive leadership team to continue its commitment to bring sophisticated clinical drug trials to the private medical practice setting" said Susan R. Waldron formerly chief executive of Prime Staff USA Clinical Research and now chief executive of Medicus Management Resources. Medicus Alliance provides the tools personnel and resources to enable private practicing physicians to participate in innovative clinical therapies historically available only in academic settings to select groups of patients.

The Galveston County Daily News
Daily News – Galveston County – Dec 24, 2007
Admin Dee and James Pratt Lynn and Jack Alperin Michele and Greg Chalhoub Jeanine and Rick Price Cheryl Proctor and Randy and Sue Urban visiting with the girls from Clinical ncology trials office Cathy Reynolds Linda Stephens Janie Hirsch Phyllis Crawford Roserika Brooks and Natia Watson. A welcome fixture at any and all holiday “Do’s” (Natch!) are Divafaves all; Julian Ramirez Amad Jones Guillermo Moreno Franci Moreno and Mary Ann Tamez of Steve Griffith’s catering. These guys keep the goodies coming and believe the Diva they are all goodies!Former General Clinical Research Center Nurse Manager Holly Paskell (and her beau Jerry Morris) holding court at 21 while visiting after having completed her master’s in nursing at UTMB. Holly’s now director of Clinical Research at the University of Texas at Tyler. Among the group were Divafave the titian-tressed Lori Wiseman (her hairstyle compliments of the master Jose Garcia) and Ragin’ Cajun Eileen Langan and her husband Lynn and Dionne Randle. Had fun with BI’s Patrice Mozie and her mom ttie Washington. Stopping for a mo were David Marshall and Curtiss and Suellen Brown… A welcome fixture at any and all holiday “Do’s” (Natch!) are Divafaves all; Julian Ramirez Amad Jones Guillermo Moreno Franci Moreno and Mary Ann Tamez of Steve Griffith’s catering. These guys keep the goodies coming and believe the Diva they are all goodies!Former General Clinical Research Center Nurse Manager Holly Paskell (and her beau Jerry Morris) holding court at 21 while visiting after having completed her master’s in nursing at UTMB. Holly’s now director of Clinical Research at the University of Texas at Tyler. Among the group were Divafave the titian-tressed Lori Wiseman (her hairstyle compliments of the master Jose Garcia) and Ragin’ Cajun Eileen Langan and her husband Lynn and Dionne Randle. Had fun with BI’s Patrice Mozie and her mom ttie Washington. Stopping for a mo were David Marshall and Curtiss and Suellen Brown. +++The Krewe of Gambrinus had its annual Christmas Party and King’s Day Celebration at the Aquarium Restaurant on the Kemah Boardwalk.

Pact on ‘bench to bedside’ research system
Hindu – Dec 22, 2007
Sri Ramachandra University (SRU) signed Memoranda of Understanding with both Anna University and the Indian Institute of Technology Madras to focus on “translational” education and research. Rapidly emerging “Translational medicine is a rapidly emerging discipline focussed on bridging technologies and discoveries in the laboratory with clinical research and practice” S. Thyagarajan director and chief research advisor Sri Ramachandra University said explaining the “bench to bedside” concept. Requirement To meet the challenges “a new breed of professionals conversant with the medical profession as well as the engineering profession is required” Anna University Vice-Chancellor D.

pen source drug discovery
Economic Times – Dec 21, 2007
Two because of the costsinvolved the new research is directed only at promising markets typicallydisease common in rich countries though some of the third world ones such asmulti-drug resistant TB have become an issue in developed countries too. This initiative promises to divert some research attention toailments common in developing countries. And importantly move research toacademia and contract-research organisations in countries such as India whereclinical research costs are much lower. The drugs developed through the processwould not be IPR-protected and would therefore become a low-cost generic fromday one. However for the idea to be successful it is essential thatthe breakthroughs are recognised and appropriately rewarded. CSIR should try torope in similar publicly funded institutions from other countries. This wouldhelp enhance the credibility of the initiative through a wider internationalparticipation.

Wyeth Will Pursue Claim for Damages Resulting From Teva Pharmaceutical…
Genetic Engineering News – Genetic Engineering News (press release) – Dec 24, 2007
The court stated that at trial the generic companies would facethe higher burden of demonstrating by clear and convincing evidence that thepatent is not valid. At trial Wyeth will seek to recover its lost profitsand other damages resulting from Teva’s infringing sales and a permanentinjunction against future sales of generic pantoprazole prior to expiration ofthe PRTNIX patent. That patent will expire in July 2010 but Wyeth’smarketing exclusivity may be extended until January 2011 as a result ofclinical research undertaken by the Company regarding the pediatric use of theproduct. Sales of PRTNIX for the first nine months of 2007 totaled approximately$1. Wyeth will hold a conference call with research analysts at 8 a.

Favorable review for RPCI frees up funding
Bizjournals.com – Dec 21, 2007
The renewal of the Cancer Center Support Grant is a multi-step competitive process in which Roswell submitted a 1100 page grant application and had an on-site visit in September 2007 from NCI peer-reviewers. To be designated a NCI comprehensive cancer center a facility must demonstrate depth and breadth of research activities in basic clinical and prevention control and population-based research as well as maintain a strong body of interactive research that bridges these scientific areas. In the area of clinical research a comprehensive cancer center must initiate and conduct early phase innovative clinical trials; and provide leadership and accrue patients to these trials. A center also must provide outreach education and information on cancer to the community it serve The peer-review team recommended that Roswell Park receive the full $4. 9 million per year it requested in its application. Funding determinations have yet to be announced by NCI. "The receipt of a superb score on the renewal of our NCI Core Grant is testament to the outstanding work of the Roswell Park team and affirms that we are committed to conducting innovative and pioneering research and providing exemplary patient care" said Dr.