Three SD companies are developing drugs to help battle obesity
The News Review:
- Three SD companies are developing drugs to help battle obesity
- Award honors entrepreneurs|
- Some Adults With Type 1 Diabetes Have Beta Cells Live Complication…
- Breakthrough for skin cancer patients
- Profile: University of Dundee
- Daily Times – Leading News Resource of Pakistan
- Duke patients settle hydraulic fluid claims
Three SD companies are developing drugs to help battle obesity
San Diego Union Tribune – Jun 19, 2008
The most frequently prescribed medication for obesity is phentermine which was approved several decades ago but never tested for long-term use they said. The executives from the three publicly traded San Diego companies pointed out that excitement has built around the experimental drugs because so many previous attempts at obesity therapies have failed. Arena has an experimental drug lorcaserin in Phase 3 trials. The pill targets the parts of the brain serotonin 2c receptors that regulate the desire for food intake said Christen Anderson vice president of clinical research. “If you look at what causes obesity it's primarily the central nervous system's regulation of what you eat and peripheral factors of what calories you are burning off” Anderson said.
Award honors entrepreneurs|
Akron Beacon Journal – Jun 19, 2008
The winners are: Baiju Shah BioEnterprise; Victoria Tifft Clinical Research Management Inc. ; Craig Shular GrafTech International Ltd. ; Tilmon Brown New Horizons Baking Co. ; David Coury Pharmacy Management Group; Michelle Tomallo and Micki Tubbs FIT Technologies; Mark Goldfarb and Gary Shamis SS&G Financial Services; and James Hummer Whole Health Management Inc. The winners are eligible for Ernst & Young’s national awards program.
Some Adults With Type 1 Diabetes Have Beta Cells Live Complication…
Science Daily – Science Daily (press release) – Jun 19, 2008
JDRF’s Chief Medical fficer Paul Strumph MD also presented findings that showed how beta cell mass expands in response to increased metabolic demands such as growth during the first decade of life obesity and pregnancy – leading to possible therapeutics that mimic the biological mechanisms that increase insulin-producing cells in this instances. "A little bit of insulin is not a cure but it can be significant to reduce the complications of diabetes" Strumph noted. A New Era of Diabetes Research Has BegunAll of the presenters agreed that researchers are on the cusp of a new era in diabetes research one in which advanced technology and human clinical research should enhance the development of new therapeutics and an ultimate cure. "Much of what we’ve known regarding the pathogenesis of type 1 diabetes has dated back to studies performed with the human pancreas’ in the 1970s — before microwaves the internet and cell phones and before modern day medical research technology. Now we’re looking at this disease in whole new ways" explained Atkinson. Strumph added that there is more of an emphasis on looking at the natural history of the disease to guide research opportunities for those with established type 1 diabetes. JDRF is currently devoting a significant portion of its $160 million in research funding to science involving people with established type 1 diabetes with a particular emphasis on areas such as autoiummunity and regeneration; the organization and plans to fund as much as $195 million on research in the coming 12 months.
Breakthrough for skin cancer patients
Independent nline – Jun 19, 2008
The ground-breaking treatment for advanced melanoma or skin cancer led to a long remission for the patient and used his own cloned infection-fighting T-cells said doctor Cassian Yee the lead author of the study in the New England Journal of Medicine. Yee and his associates from the Clinical Research Division at Fred Hutchinson Cancer Research Centre in Seattle removed CD4+ T-cells a type of white blood cell from a 52-year-old man whose melanoma had spread to a groin lymph node and to one of his lungs. The melanoma was already well advanced and in stage four. The T-cells which specifically fight melanoma were modified and expanded in the laboratory and some five billion cells were then infused into the patient who received no other kind of treatment. Two months later no tumours were found during scans of the patient’s organs. And he has been cancer free for two years Yee said.
Profile: University of Dundee
Times nline – Jun 19, 2008
Almost £40 million of this is being spent on wirelessnetworked studentresidences. Best-known for the life sciences where research into cancer anddiabetes is recognised as world-class the university has already opened newbuildings for interdisciplinary research applied computing and clinicalresearch. The main library is being extended and the Faculty of Education and SocialWork acquired new premises in 2007. Set in 20 acres of parkland the medicalschool is the one of the few components of the university outside thecompact citycentre campus – some of the nursing and midwifery students are35 miles away in Kirkcaldy while education and social work are waiting tomove from the former Northern College campus two miles outside the centre. StrengthsBiochemistry is the flagship department housed in the £13-million WellcomeTrust Building. Its academics were the first in Britain to be invited totake part in Japan’s Human Frontier science programme and are now themostquoted researchers in their field.
Daily Times – Leading News Resource of Pakistan
Daily Times – Jun 19, 2008
For heart-related deaths ibuprofen was linked to three extra deaths per 1000 patients treated per year. However Wyeth Consumer Healthcare the maker of Advil said “this study does not provide a definitive answer” to whether ibuprofen interferes with the effects of aspirin. Wyeth spokesman Fran Sullivan argued that recent clinical research papers “suggest that the use of ibuprofen at the same time as low-dose aspirin does not alter the risk from heart disease. “Dr Tom MacDonald who led the Lancet study said taking the odd ibuprofen for a few days would not be a problem. It’s regular use that seems to be at issue. Dr Veronique Roger head of cardiovascular research at the Mayo Clinic in Rochester Minnesota who was not connected to the study said it could be that heart patients who take ibuprofen have additional conditions that in turn make them more prone to premature death and were not accounted for in the study she noted.
Duke patients settle hydraulic fluid claims
News & bserver – Jun 19, 2008
A Superior Court judge rules that patients in question can seek high-dollar punitive damages. SEPTEMBER 2005: Results from an independent laboratory say heavy metals that can cause cancer and microscopic particles of carbon and machinery metal were found in the hydraulic oil waste at Duke. NVEMBER 2005: Duke hires PharmaLinkFHI an independent clinical research organization in Durham to monitor the health of patients who were exposed to tainted surgical instruments. html –> More Home.
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