The News Review:

- The undeniable impact of biomedical research
- PHC Completes Sale of Pivotal Research Centers For $5 Million
- Medical clinical research slows for lack of patients
- Less of a stink in diabetes patients?
- » Clinical Research Associate
- ACR Statement Regarding Nomination of Dr. Margaret A. Hamburg as …
- 10-K: NEXMED INC

The undeniable impact of biomedical research
Fort Worth Business Press
Today thanks to pioneering research they’re almost non-existent and the benefits are obvious both in terms of healthier worldwide populations and attendant increases in productivity. And as new therapies reduce the number of patients needing treatment and lower the overall cost of per-patient treatment social benefits accrue exponentially. To evaluate the economic value of medical research to society we might begin by defining two broad categories: “clinical research” the evaluation of new treatments for safety and efficacy in clinical trials with patients; and “translational research” which combines basic laboratory research (theory and animal experiments) with clinical research results and contributes to the development of new treatments. And at the risk of blowing our own horn I think that Tarrant County can take justifiable pride in the fact that the University of North Texas Health Science Center excels at both types of research. For example earlier this month the UNT Health Science Center celebrated its 17th annual Research Appreciation Day an institutional tradition encompassing medicine public health and basic science. The event featured about 200 research projects on a range of heath issues including aging Alzheimer’s disease cancer cardiovascular disease diabetes vision osteopathic manipulative medicine physical medicine women’s health public health and infectious diseases. This research invaluable in its own right also is an economic spark plug: According to the U.

PHC Completes Sale of Pivotal Research Centers For $5 Million
Business Wire (press release)
The company focuses its research and development program on enhancing software systems used to support its clinical trials management and information services. Its services include dedicated clinical sites medical and safety management medical writing data management biostatistics interactive voice response systems regulatory affairs and quality assurance. The company conducts its clinical research in the areas of infectious diseases oncology pediatrics analgesia and central nervous disorders. Premier Research Group plc was founded in 2002 and is based in Crowthorne the United Kingdom. The company also offers internet and telephonic-based referral services that includes employee assistance programs and critical incident services.

Medical clinical research slows for lack of patients
Los Angeles Times
James Thomas director of clinical trials at the hio State University Comprehensive Cancer Center says some insurance policies don’t pay for blood tests scans or examinations linked to the treatment. Medical clinical research slows for lack of patientsJay LaPrete For The TimesDr. James Thomas director of clinical trials at the hio State University Comprehensive Cancer Center says some insurance policies don’t pay for blood tests scans or examinations linked to the treatment. Enrollment shortages have delayed or canceled trials on experimental therapies. Researchers are trying to reverse that trend in part by using databases to connect patients with possible new cures.
Related from Cnurology: FDA Approves Ferring Pharmaceuticals’ Degarelix (Generic Name) for …

Less of a stink in diabetes patients?
EurekAlert (press release)
In the case of diabetes common complications of the disease are high blood pressure and microvascular dysfunction which leads to damage of the tiny blood vessels (microvessels) that deliver blood oxygen and nutrients to the eyes skin nerves and kidney. Matt Whiteman of the Peninsula Medical School and colleagues from the Peninsula National Institute for Health Research (NIHR) Clinical Research Facility have compared the levels of H2S in blood samples taken from healthy people and male patients with type II diabetes and found markedly decreased levels of H2S in the diabetes patients. Lower H2S levels were associated with clinical markers of impaired microvessel function suggesting that a loss of this blood pressure lowering gas could be a contributing factor in the development of vascular complications in patients with diabetes. Previous work on H2S has almost exclusively been carried out on animals in the laboratory however work carried out at PMS in the recently opened Peninsula NIHR Clinical Research Facility has been the first to investigate the role of H2S in any disease in humans. Whiteman commented: “ur previous work in the test tube has shown the potential for H2S to mediate blood pressure regulation.

» Clinical Research Associate
Hays Pharma
You can find more stories like this at Hayspharma. comFriend email addressSend emailRelated NewsPfizer drug ‘improves survival rates forPfizer’s Sutent drug has been found to significantly extend progression-free survival for patients.

ACR Statement Regarding Nomination of Dr. Margaret A. Hamburg as …
Business Wire (press release)
ACR salutes the public service of Drs. Hamburg and Sharfstein and we look forward to working with them in their new roles. About ACR The Association of Clinical Research rganizations (ACR) is the professional organization of companies whose focus is clinical research. The association provides an active voice for the CR industry which provides specialized services that are integral to the development of drugs biologics and medical devices. ACR helps its members improve the quality efficiency and safety of biomedical research. ACR member companies employ more than 70000 professionals worldwide. For more information please visit.

10-K: NEXMED INC
MarketWatch (press release)
The following table summarizes our contractual obligations and the periods in which payments are due as of December 31 2008: Less than 1 – 3 3 – 5 More thanContractual bligations Total 1 year years years 5 years Long-term debt * $ 5510750 $ 328300 $ 5182450 $ 0 $ 0 Purchase obligations ** 592000 592000 0 0 0 ther long-term liabilities*** 1228800 109900 329700 329700 459500 Total $ 7331550 $ 1030200 $ 5512150 $ 329700 $ 459500 * Long-term debt consists of a convertible note secured by a mortgage totaling $4. 69 million plus all related interest. ** Purchase obligations consist of a penalty fee for a clinical research agreement that was cancelled on September 30 2008. The penalty for our cancellation of this $4182700 agreement was approximately $892000. ff-Balance Sheet Arrangements We do not have any off-balance sheet arrangements. Critical Accounting Estimates ur discussion and analysis of our financial condition and results of operations is based upon our consolidated financial statements which have been prepared in accordance with accounting principles generally accepted in the United States of America. Note 2 in the Notes to the Consolidated Financial Statements includes a summary of the significant accounting policies and methods used in the preparation of our Consolidated Financial Statements.