The News Review:

- » Senior Clinical Research Associate
- Study examines reliability of clinical and pathological diagnoses …
- Psychiatric Drugs Might Raise Cardiac Death Risk
- Feasibility Studies For Health Research Announced
- Survey: Many Women Slip on Bone Health
- alphavax Announces Full Enrollment in Phase I/II Study of Active …
- Clinical Research Casts Doubt n Accuracy f besity Measurements

» Senior Clinical Research Associate
Hays Pharma
00 per annumLocationSweden15 May 2009Are you tired of travelling to the office and would you enjoy the flexibility of being home based? My client a well-reputed and rapidly growing international Clinical Research rganisation which is looking for an experienced Clinical Research Associate to join them and develop your career within the organisation. They are looking for people with the right mix of experience professionalism and a friendly personality in Denmark Sweden Norway and Finland. As a home based Clinical Research Associate your core responsibilities will include site selection designing and conducting clinical studies initiation monitoring and close-out visits where necessary. You will also play a key role in multidisciplinary study and project teams to ensure that key result areas are achieved and activities are optimised. You will have knowledge of relevant regulations and guidelines to ensure that trials are conducted to appropriate internal and external standards.

Study examines reliability of clinical and pathological diagnoses …
EurekAlert (press release)
The authors emphasized that the proportion of patients confirmed to have Barrett’s esophagus likely represents the minimum number given the strict criteria used. Researchers concluded that electronic coding alone overestimates the prevalence of Barrett’s esophagus and most clinical and research uses will require a manual verification of disease status. These results can help inform diagnoses of Barrett’s esophagus for patient care health policy and clinical research. An accompanying editorial by Joel H. Rubenstein MD MSc Veterans Affairs Center for Clinical Management Research Division of Gastroenterology University of Michigan Medical School Ann Arbor appears in the May issue and offers steps endoscopists and pathologists can take regarding the diagnosis of Barrett’s esophagus. ###About the American Society for Gastrointestinal EndoscopyFounded in 1941 the mission of the American Society for Gastrointestinal Endoscopy is to be the leader in advancing patient care and digestive health by promoting excellence in gastrointestinal endoscopy. ASGE with nearly 11000 members worldwide promotes the highest standards for endoscopic training and practice fosters endoscopic research recognizes distinguished contributions to endoscopy and is the foremost resource for endoscopic education.

Psychiatric Drugs Might Raise Cardiac Death Risk
Atlanta Journal Constitution
The findings “are interesting even provocative but much more work remains to be done in order to have a high degree of confidence in the results” said Dr. Harrington director of the Duke Clinical Research Institute in Durham N. “For now society should insist upon randomized clinical trials during and after the drug approval process that test therapies in patients who will likely take the drugs in ‘real life’” Harrington said. That means those who take part in tests of drugs represent those who ultimately take them when it comes to their medical conditions and the other drugs that they’re taking he explained. More informationLearn more about sudden cardiac death from the.

Feasibility Studies For Health Research Announced
Voxy
The HRC is the principal Government agency responsible for funding health research in New Zealand. ne million dollars is allocated from the HRC’s Investment Strategy to fund Feasibility Studies in the fields of public health or clinical research. f the five that have received funding one was Maori health research one was clinical research and three were public health research. “The studies are important ground work that will help decide if larger investment in these particular projects is warranted” says HRC Chief Executive Dr Robin lds. Feasibility Studies are carried out to test issues affecting a planned larger study. The projects address whether the proposed choice of methodologies is appropriate the likelihood of obtaining valid results and acceptability in a population.
Related from 9p2cn: Joint feasibility study

Survey: Many Women Slip on Bone Health
WebMD
After survey participants reviewed educational information about osteoporosis nearly three quarters of women with osteoporosis reported that they plan to make their bone health more of a priority. The Know My Bones Council includes the National steoporosis Foundation the Society for Women?s Health Research and Amgen a company that manufactures medicines. ?As women retire later bone health is not a luxury it is a necessity? says Felicia Cosman MD clinical director of the National steoporosis Foundation and medical director of the Clinical Research Center at Helen Hayes Hospital. ?Although some women are making significant strikes toward better bone health many are not and need to do more. ? Archelle Georgiou MD a member of the Society for Women?s Health Research board of directors says that because four out of five people with osteoporosis are women it?s critical for them to make healthy bones a priority effort. ?We are pleased to see that after learning about the risks of osteoporosis as part of the survey many women reported that they would take action to make bone health more of a priority by speaking with their doctor re-evaluating their bone density scores and educating themselves and others? she says in a news release. May is steoporosis Awareness and Prevention Month.

alphavax Announces Full Enrollment in Phase I/II Study of Active …
SYS-CN Media (press release)
CEA-expressing VRP were administered by intramuscular (IM) injection every 3 weeks for a minimum of 4 immunizations with additional doses in patients without progressive disease every 3 months. “We have now enrolled the 24 patients targeted for this study and while this is obviously not the size or kind of study upon which conclusions can be drawn it appears to have a favorable tolerability and safety profile which will need to be much more fully evaluated in larger clinical trials” stated Dr. Michael Morse Principal Clinical Investigator on the study and Medical Co- Director of Duke Clinical Research – ncology (DCR). “We are excited to be in clinical trials with this immunotherapy product that has shown promising ability to break tolerance against the CEA tumor antigen in pre-clinical studies. This trial marks the first immunotherapeutic clinical study of our alphaviral vector delivery platform and we are hopeful the robust immune responses we have seen in multiple prophylactic vaccine studies are similarly elicited in these cancer patients” said Dr. Jonathan Smith CS at AlphaVax. Colorectal cancer is the most common cancer that expresses CEA.

Clinical Research Casts Doubt n Accuracy f besity Measurements
Medical News Today (press release)
Now the latest results in the ongoing research aimed at validating its use in a medical context are showing more accuracy than results from using a tape measure. Following the first clinical research for the validation of BVI undertaken by Heartlands NHS Hospital in Birmingham England Mayo Clinic in Rochester Minnesota USA has presented its own research comparing manual and computer measurements. In a study of 80 patients under strict observational and scientific conditions waist and hip measurements taken manually and by a 3D BVI Body Scanner were compared highlighting significant variances between using a tape measure and the scanner. The two variables were obtained by taking two measurements from the same patient at intervals either manually or by 3D scan and then comparing the differences between the same measurement techniques in terms of their reproducibility to see which was the more accurate. All measurements were taken with at least one observer present. The mean difference for the waist measured manually was 3.